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Filtered Search Results
Medchemexpress LLC m-PEG3-CH2CH2COOH | 67319-28-2 | MFCD11041124 | 97.0% | 236.26 g·mol⁻¹ | C10H20O6 | 5 G
m-PEG3-CH2CH2COOH is a methoxy-terminated PEG3 carboxylic acid used as a short, flexible spacer for bioconjugation chemistry. It is employed as a non-cleavable linker in antibody-drug conjugate (ADC) assembly and as a PEG-based linker in PROTAC and other conjugation workflows, providing a terminal carboxylic acid for coupling reactions and improving solubility of conjugates.
- Methoxy-terminated PEG3 spacer providing flexibility.
- Terminal carboxylic acid suitable for amide coupling and esterification.
- Molecular weight 236.26 g·mol⁻¹ for predictable spacer length.
- High purity (approximately 97.0%) suitable for research applications.
- Available in small research-scale quantities and recommended refrigerated storage for stability.
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Medchemexpress LLC GSK2807 trifluoroacetate | 2245255-66-5 | 99.8% | 566.53 g/mol | C21H33F3N8O7 | 50 MG
GSK2807 trifluoroacetate is a selective, SAM-competitive inhibitor of the protein methyltransferase SMYD3 with potent biochemical activity (Ki = 14 nM; IC50 = 130 nM). Supplied as the trifluoroacetate salt and formulated for research applications, it is intended for biochemical and cellular studies of SMYD3-mediated methylation and epigenetic regulation.
- Provided as a trifluoroacetate salt for improved handling
- Potent SMYD3 inhibition (Ki 14 nM; IC50 130 nM)
- High purity suitable for research use
- Compact 50 mg package size for assay development
- Well characterized for biochemical and cellular studies
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Apexbio Technology LLC Epidermal Growth Factor Receptor Peptide (985-996) 96249-43-3 10mg
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Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3) corresponds to a C-terminal segment of the EGFR protein involved in receptor autophosphorylation EGFR a transmembrane receptor tyrosine kinase undergoes activation upon ligand binding triggering receptor dimerization and subsequent phosphorylation of specific tyrosine residues within its C-terminus including the 985-996 region This phosphorylation facilitates recruitment of SH2 domain-containing signaling proteins thereby initiating pathways such as MAPK Akt and JNK which regulate cell proliferation migration and adhesion This peptide serves as a useful research tool for elucidating EGFR-mediated signaling and studying kinase-substrate interactions in cellular models
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Medchemexpress LLC (S,R,S)-AHPC-PEG3-NH2 hydrochloride | 2097971-11-2 | MFCD31656714 | >95.0% | 656.23 | C30H46ClN5O7S | 2 G
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(S,R,S)-AHPC-PEG3-NH2 hydrochloride is a VHL E3 ligase ligand-linker conjugate supplied as the hydrochloride salt for use in PROTAC development and related chemical biology research. It is a PEG3-linked derivative of the AHPC VHL ligand and is provided in multiple packaged sizes for synthesis and assay workflows.
- VHL E3 ligase ligand-linker conjugate suitable for PROTAC design.
- Provided as the hydrochloride salt for improved solubility and handling.
- Available in multiple sizes, including 2 G.
- Molecular formula C30H46ClN5O7S; molecular weight 656.23.
- Purity ≥95% by supplier specification.
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Medchemexpress LLC Trimethylammonium chloride-d6 | 347840-14-6 | MFCD11036246 | 99.4% | 101.61 | C3H4D6ClN | 5mg
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Trimethylammonium chloride-d6 is the deuterium labeled Trimethylammonium chloride[1] Trimethylammonium chloride is an endogenous metabolite
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378623 GGTI298 TRIFLUOROAC 10MM 1ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000387488 PS-1145 100MG
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eMolecules 1-Bromo-2-(3-bromopropoxy)benzene | 37136-84-8 | MFCD02030868 | 1g
Combi-Blocks | 1-Bromo-2-(3-bromopropoxy)benzene | 1g | 228814155 | OT-0617 | 97.000 | 37136-84-8 | MFCD02030868 | 293.986 | C9H10Br2O
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Gelest Inc 1 1 1 3 3 3-HEXAMETHYLDISILAZA
This item has a minimum qty of 14 per supplier requirements.
1 1 1 3 3 3-HEXAMETHYLDISILAZA
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eMolecules {3-[(tert-butyldimethylsilyl)oxy]cyclobutyl}methanol | 1394119-83-5 | MFCD23106334 | 1g
Pharmablock | {3-[(tert-butyldimethylsilyl)oxy]cyclobutyl}methanol | 1g | 551073908 | PB05119 | | 1394119-83-5 | MFCD23106334 | 216.396 | C11H24O2Si
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Medchemexpress LLC HYDROXY-PEG3-CH22-BO 10G
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5000202876 HYDROXY-PEG3-CH22-BO 10G
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Medchemexpress LLC 5,8,11-trioxa-2-azatridecanoic acid, 13-hydroxy-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester | 2126749-77-5 | 99.6% | 369.45 g/mol | C19H31NO6 | 25 MG
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BCN-PEG3-OH is a BCN-functionalized, 4-unit polyethylene glycol (PEG) linker and click-chemistry reagent used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis. It contains a bicyclo[6.1.0]non-4-yne (BCN) group that reacts via strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized molecules, enabling efficient bioconjugation.
- Non-cleavable 4-unit PEG linker for ADC synthesis.
- BCN group enables SPAAC click chemistry with azides.
- High purity (99.6% by LCMS).
- Light yellow oil appearance.
- Stored at -20°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
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Medchemexpress LLC (S,R,S)-Ahpc-C6-Peg3-C4-Cl | 1835705-55-9 | MFCD31560478 | ≥95.0% | 751.42 g/mol | C38H59ClN4O7S | 500 MG
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(S,R,S)-AHPC-C6-PEG3-C4-Cl is a VHL ligand-linker conjugate used as a building block in targeted protein degradation (PROTAC) research. It supplies a halide-terminated PEG linker designed for coupling in degrader synthesis and related medicinal chemistry applications.
- Used as a VHL ligand-linker building block for PROTAC synthesis.
- Molecular formula C38H59ClN4O7S.
- Molecular weight 751.42 g/mol.
- Purity ≥95.0% (manufacturer assay).
- Supplied as a 500 mg solid.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Broadpharm / m-PEG8-triethoxysilane / 250mg / 795361866 / BP-40222 / 95.000 / / [null] / 615.833 / C27H57NO12Si
Broadpharm / m-PEG8-triethoxysilane / 250mg / 795361866 / BP-40222 / 95.000 / / [null] / 615.833 / C27H57NO12Si
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SB290157 trifluoroacetate | 1140525-25-2 | MFCD04974198 | 99.8% | 526.51 g·mol⁻¹ | C24H29F3N4O6 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SB290157 trifluoroacetate is the trifluoroacetate salt of SB290157, a potent and selective antagonist of the complement component 3a receptor (C3aR). It is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) for in vitro research applications investigating C3aR-mediated signaling pathways.
- Potent C3a receptor antagonist (IC50 200 nM).
- Supplied as a 10 mM solution in DMSO, 1 mL.
- High purity (~99.8%) suitable for biochemical assays.
- Molecular weight 526.51 g·mol⁻¹ for the trifluoroacetate salt.
- Formulated as a trifluoroacetate salt to aid solubility in organic solvents.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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